Joel Linden - Charlottesville VA
Heidi Taylor - Charlottesville VA
Anna Robeva - Charlottesville VA
Robin Woodard - Palmyra VA
Xiaowei Jin - Charlottsville VA
The University of Patent Foundation - Charlottesville VA
Stable over-expression of native and hexahistidine/FLAG extended recombinant human adenosine receptors permits recovery of membranes and membrane fragments bearing a high density of adenosine receptors. Cell lines expressing all four sub-types of human adenosine receptors have been identified. The receptors, and membranes and membrane fragments bearing the same, can be used in assays to screen compounds for binding ability to the adenosine receptors, such as potential pharmaceutical agents.